Toward Normative Expert Systems Part II

Methods of Information in Medicine | , Vol 31: pp. 106-116

Publication

Part II. Probability-based representations for efficient knowledge acquisition and inference

We address practical issues concerning the construction and use of decision-theoretic or normative expert systems for diagnosis. In particular, we examine Pathfinder, a normative expert system that assists surgical pathologists with the diagnosis of lymphnode diseases, and discuss the representation of dependencies among pieces of evidence within this system. We describe the belief network, a graphical representation of probabilistic dependencies. We see how Pathfinder uses a belief network to construct differential diagnoses efficiently, even when there are dependencies among pieces of evidence. In addition, we introduce an extension of the belief-network representation called a similarity network, a tool for constructing large and complex belief networks. The representation allows a user to construct independent belief networks for subsets of a given domain. A valid belief network for the entire domain can then be constructed from the individual belief networks. We also introduce the partition, a graphical representation that facilitates the assessment of probabilities associated with a belief network. Finally, we show that the similarity-network and partition representations made practical the construction of Pathfinder.