Phenotypes, Genotypes and Environmental Factors in Childhood Asthma
We are working in collaboration with the Manchester Asthma and Allergy Study (MAAS) and Shared Genomics project to gain a better understanding of the genetic and environmental causes of childhood asthma. An important part of this work is to explore the phenotypes exhibited by children suffering from asthma, the underlying assumption being that asthma actually corresponds to a group of diseases with similar, but not identical, phenotypes.
Publications
- A. Simpson, V.Y. Tan, J. Winn, M. Svensen, C.M. Bishop, D.E. Heckerman, I. Buchan, and A. Custovic, Beyond Atopy: Multiple Patterns of Sensitization in Relation to Asthma in a Birth Cohort Study, in Am J Respir Crit Care Med, 18 February 2010
