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Jasmin Fisher

 Ph.D. Weizmann Institute of Science, 2003

Senior Researcher at Microsoft Research Cambridge in the Programming Principles and Tools group

Research Group Leader at the Department of Biochemistry in University of Cambridge

Member of Cambridge Cancer Centre and Cambridge Systems Biology Centre 

Executable Biology

Our research focuses on the design and analysis of executable computer algorithms describing biological phenomena, in particular cancer biology. We call this approach Executable Biology. These kinds of models hold great promise for new discoveries in a wide variety of biological systems. Once an executable model has been built of a particular system, it can be used to get a global dynamic picture of how the system responds to various perturbations. In addition, preliminary studies can be quickly performed using executable models, saving valuable laboratory time and resources for only the most promising avenues.

Research Overview

Our work is focused on two main directions:  

(1) The use of different formalisms to create executable models of biological phenomena, aiming to gain new insights into the molecular mechanisms underlying the fundamental question of cell fate determination (or in other words - how cells make the decision to develop into a particular cell type) during the course of normal development (e.g., our work on blood stem cells development), and cancer (e.g., stem cell differentiation in mammalian epidermis, EGFR/Notch/Wnt crosstalk in cancer cells, regulation of leukemic blood stem cells).

(2) The development of tools and design of algorithms that are specifically tailored for modelling and analyzing biological networks (e.g., bounded-asynchrony, synthesis algorithms for gene regulatory networks). We put a lot of emphasis on constructing user-friendly tools (i.e., visual, flexible), in order to facilitate the integration of such computational tools as mainstream techniques in biological and medical research (e.g., Bio Model Analyzer).


Group Members

  • Steven Woodhouse (Ph.D. student, University of Cambridge, joint with Bertie Gottgens)
  • Matthew Clarke (PhD student, University of Cambridge)
  • Chee Yee Lim (PhD student, University of Cambridge, joint with Bertie Gottgens)
  • Dana Silverbush (PhD student, Tel-Aviv University)
  • Mrigya Agarwal (MSc student, ETH, intern MSRC)
  • Moritz Reiterer (MSc student, University of Cambridge)
  • Felicia Ng (post-doc, University of Cambridge, joint with Bertie Gottgens)
  • Ben Hall (BMA team, MSRC)
  • Nir Piterman (BMA team, MSRC)
  • David Benque (BMA team, MSRC)
  • Alex Taylor (BMA team, MSRC)
  • Scarlet Schwiderski-Grosche (BMA team, MSRC)
  • Nikita Skoblov (BMA team, MSRC)
  • Sergey Berezin (BMA team, MSRC)

Former Post-docs & Students

  • Marc Schaub (M.Sc. student, EPFL, 2005-2006)
  • Dennis Wang (M.Sc. student, Cambridge University, 2008)
  • Antje Beyer (M.Sc. student, Cambridge University, 2008)
  • Maria Mateescu (Ph.D. student, EPFL, joint with Tom Henzinger, 2006-2009)
  • Luke Church (Ph.D. student, Cambridge University, 2007-2009)
  • Avital Sadot (Post-doc, joint with David Harel, 2007-2010)
  • Garth Ilsley (Ph.D. student, EBI, Cambridge, 2007-2010)
  • Peter Ackermann (M.Sc. student, Cambridge University 2011, joint with Steve Oliver)
  • Lucinda Moore (M.Sc. student, Cambridge University 2012, joint with Bertie Gottgens)
  • Ryan Chuang (M.Sc. student, Cambridge University 2012, joint with Bertie Gottgens)
  • Antje Beyer (Ph.D. student, Cambridge University 2009-2012)
  • Ariel Feiglin (Ph.D. student, Bar-Ilan University, joint with Yanay Ofran)
  • Anthony Gitter (post-doc, MSR-NE, 2012-2014)
  • Ben Hall (post-doc, MSRC, 2012-2014)
  • Victoria Wang (MSc student, University of Cambridge 2015, joint with Gerard Evan)
  • Ali Sinan Koksal (Ph.D. student, UC Berkeley, joint with Ras Bodik)


In the press


If you are seeking a postdoctoral, PhD or MSc position and have an interest in joining our lab, please send your CV including a statement of interests to jasmin.fisher ''at''


Dr. Jasmin Fisher
Microsoft Research Cambridge
21 Station Road
Cambridge CB1 2FB, UK
Phone: +44-1223 479 947
Fax: +44-1223 479 999
Email: jasmin.fisher"at"