The Microsoft Biology Foundation (MBF) 2.0 beta is a language-neutral bioinformatics tool kit built as an extension to the Microsoft .NET Framework. It implements a range of parsers for common bioinformatics file formats; a range of algorithms for manipulating DNA, RNA, and protein sequences; and a set of connectors to biological web services such as the U.S. National Center for Biotechnology Information’s Basic Local Alignment Search Tool. MBF is available under an Open Systems Interconnection model-approved open-source license, and executable, source code, demo applications, and documentation are freely downloadable.
Note: By installing, copying, or otherwise using this software, you agree to be bound by the terms of its license. Read the license.
Here’s what’s new in this release:
- Increased capacity for de novo assembly of larger and more complex species than version 1.0
- Addition of comparative assembly functions for characterizing genetic diversity within or between species
- Core object model improvements for smaller memory footprint and increased parallel processing
- Parity with all version 1.0 tools and features
- Documentation updates
To run this software, you need the following:
- Windows XP with Service Pack (SP) 3 or later
- Microsoft .NET Framework version 4.0
- Copy the MBF installer to a folder on your hard drive.
- Navigate to that folder and double-click Setup_Framework.msi, which runs the installation wizard.
- Follow the directions in the installation wizard to install MBF.
The MBF installer creates a directory named C:\Program Files (x86)\Microsoft Biology Initiative\0.2\MBF that contains the following:
If you install the optional SDK, the installer creates an SDK folder in the MBF folder that contains the following:
For more information, see MBF documentation.